MIGHT THERE BE ABUSE OF GENETIC THERAPY?
Of course, there are concerns regarding gene therapy. New choices will be available to us which many will find difficult - or objectionable. Changing DNA can be a very emotive issues. Issues about whether to permit or deny life itself will have to be confronted.

But life-and-death decisions have been made by doctors - covertly - ever since medicine began. Being able to manipulate DHA does not change that. The exact time to turn off a life-support machine, for example, is an unenviable, and often purely subjective, choice for the medical profession. The choice is made even more difficult because occasional cases of completely unexpected emergence from coma have occurred.

Soon, though, we will have the ability to manipulate human life, through the DNA, more than ever before. Yes, we will be able to replace disease-producing genes before, or just after, birth. Obviously, if we could choose between our baby having a particular birth 'defect' or not, most of us would prefer our child to be free of it.

But also we will have the ability to introduce genes to make 'improved' humans. These could include raising IQ, choosing hair colour, or deciding the size of particular muscles, for example. Most governments will ban the obviously distasteful options; but society has to decide exactly where to draw the line. And will some of the more secretive governments of the world be more lax in their regulations?

In the 1960s and 70s, some Eastern European countries persuaded their sportsmen and women to use anabolic steroids from a dangerously early age, to boost athletic performance. This risked their lives and health. Will some athletes of the future be genetically 'bred for success' by the unscrupulous? The temptation to modify DNA to produce physical attributes will be there.

THE SECRET OF ETERNAL LIFE?
And what about old age? No reason has been found for the aging process. The body re-creates nearly all of its cells within seven years. Why doesn't it create brand new ones each time - so that aging would not occur? We know some of the mechanisms which produce aging - but why are these mechanisms in place? Nobody really knows.

Some genes are certainly involved in producing aging. The genes which produce aging of the skin have already been identified. By manipulating these and other genes will we eventually be able to choose the length of life we enjoy/endure? Scientists have already made human cells live for double their normal lifespan. They have lengthened the lifespan of simple organisms. This type of science will certainly be applied to man.

One thing is certain - genetic therapy and gene manipulation is going to throw up some brand new questions. We have no choice but to confront them head on.

GENE THERAPY IS HERE TO STAY
We must focus on the good that gene therapy will bring - while accepting that it will not all be good. We have to take things very slowly while we decide on the safeguards which will be necessary.

We have to keep our fingers crossed - but then the human race is used to that.

The human race is about to take a huge step into gene therapy. It is almost with us. There is now no going back.

LINKS:
Resources about all aspects of genetics:
www.kumc.edu/gec/

Longevity:
pcbs042.open.ac.uk/future/Millennium/842.htm

Aging and Genetics:
www.biorap.org/rg/rgagepd.html

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